What is a known risk factor for sepsis in neonates?

Chorioamniotitis is associated with an increased risk of sepsis in neonates due to the transplacental transmission of pathogens. When the amniotic membranes are infected, it can lead to maternal fever and a more hostile environment for the fetus, increasing the likelihood of bacterial colonization and subsequent infection after birth. This condition often signifies prolonged exposure to bacteria, which can compromise the newborn's immune response and make them more susceptible to sepsis.

While maternal diabetes can influence neonatal outcomes and fetal monitoring is critical for assessing the well-being of the fetus, they are not directly established as significant risk factors for sepsis in the same manner that chorioamniotitis is. Excessive antenatal care assists in identifying potential risks but does not inherently raise the danger of sepsis in neonates. In contrast, chorioamniotitis is a direct risk factor leading to potential infection in the neonate, making it an important consideration in neonatal intensive care practice.